Conformational change in the chromatin remodelling protein MENT.

Chromatin condensation to heterochromatin is a mechanism essential for widespread suppression of gene transcription, and the means by which a chromatin-associated protein, MENT, induces a terminally differentiated state in cells. MENT, a protease inhibitor of the serpin superfamily, is able to under...

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Bibliographic Details
Main Authors: Poh Chee Ong, Sarah J Golding, Mary C Pearce, James A Irving, Sergei A Grigoryev, Debbie Pike, Christopher G Langendorf, Tanya A Bashtannyk-Puhalovich, Stephen P Bottomley, James C Whisstock, Robert N Pike, Sheena McGowan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2648895?pdf=render