Ligand-Mediated Biofilm Formation via Enhanced Physical Interaction between a Diguanylate Cyclase and Its Receptor

The bacterial intracellular second messenger, cyclic dimeric GMP (c-di-GMP), regulates biofilm formation for many bacteria. The binding of c-di-GMP by the inner membrane protein LapD controls biofilm formation, and the LapD receptor is central to a complex network of c-di-GMP-mediated biofilm format...

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Bibliographic Details
Main Authors: David Giacalone, T. Jarrod Smith, Alan J. Collins, Holger Sondermann, Lori J. Koziol, George A. O’Toole
Format: Article
Language:English
Published: American Society for Microbiology 2018-07-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.01254-18