Central role of cellular senescence in TSLP-induced airway remodeling in asthma.

BACKGROUND:Airway remodeling is a repair process that occurs after injury resulting in increased airway hyper-responsiveness in asthma. Thymic stromal lymphopoietin (TSLP), a vital cytokine, plays a critical role in orchestrating, perpetuating and amplifying the inflammatory response in asthma. TSLP...

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Bibliographic Details
Main Authors: Jinxiang Wu, Fangzheng Dong, Rui-An Wang, Junfei Wang, Jiping Zhao, Mengmeng Yang, Wenbin Gong, Rutao Cui, Liang Dong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3805661?pdf=render