Cellular and molecular mechanisms underlying the strong neonatal IL-12 response of lamb mesenteric lymph node cells to R-848.

BACKGROUND: Comparative studies on the response of neonates and adults to TLR stimulation have been almost exclusively limited to comparisons of human neonatal cord blood cells with peripheral blood from adults, and analyses of spleen cell responses in mice. We need to extend these studies and gain...

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Bibliographic Details
Main Authors: Stéphanie Ferret-Bernard, Aude Remot, Sonia Lacroix-Lamandé, Coralie Metton, Nelly Bernardet, Françoise Drouet, Fabrice Laurent
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2965667?pdf=render