MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana.

MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana.

In this study we generated a novel dual specific phosphatase 4 (DUSP4) deletion mouse using a targeted deletion strategy in order to examine the role of MAP kinase phosphatase-2 (MKP-2) in immune responses. Lipopolysaccharide (LPS) induced a rapid, time and concentration-dependent increase in MKP-2...

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Bibliographic Details
Main Authors: Mashael S Al-Mutairi, Laurence C Cadalbert, H Adrienne McGachy, Muhannad Shweash, Juliane Schroeder, Magdalena Kurnik, Callum M Sloss, Clare E Bryant, James Alexander, Robin Plevin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2978729?pdf=render

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http://europepmc.org/articles/PMC2978729?pdf=render

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