Delivery of Anti-miRNA-221 for Colorectal Carcinoma Therapy Using Modified Cord Blood Mesenchymal Stem Cells-Derived Exosomes

Delivery of Anti-miRNA-221 for Colorectal Carcinoma Therapy Using Modified Cord Blood Mesenchymal Stem Cells-Derived Exosomes

Background: Exosomes, as natural intercellular information carriers, have great potential in the field of drug delivery. Many studies have focused on modifying exosome surface proteins to allow drugs to specifically target cancer cells.Methods: In this study, human cord blood mesenchymal stromal cel...

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Bibliographic Details
Main Authors: Siqi Han, Guangchao Li, Meng Jia, Yulu Zhao, Chenglong He, Mengxi Huang, Longwei Jiang, Meijuan Wu, Jiahe Yang, Xiaoqin Ji, Xiaobei Liu, Cheng Chen, Xiaoyuan Chu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
anti-miRNA oligonucleotides
anti-miRNA-221
iRGD nanoparticles
delivery platform
exosomes
human cord blood mesenchymal stromal cells
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.743013/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2021.743013/full

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