Molecular Pathogenesis of Pancreatic Ductal Adenocarcinoma: Impact of <i>miR-30c-5p</i> and <i>miR-30c-2-3p</i> Regulation on Oncogenic Genes

Molecular Pathogenesis of Pancreatic Ductal Adenocarcinoma: Impact of <i>miR-30c-5p</i> and <i>miR-30c-2-3p</i> Regulation on Oncogenic Genes

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive types of cancer, and its prognosis is abysmal; only 25% of patients survive one year, and 5% live for five years. MicroRNA (miRNA) signature analysis of PDAC revealed that both strands of pre-<i>miR-30c</i> (<i>m...

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Bibliographic Details
Main Authors: Takako Tanaka, Reona Okada, Yuto Hozaka, Masumi Wada, Shogo Moriya, Souichi Satake, Tetsuya Idichi, Hiroshi Kurahara, Takao Ohtsuka, Naohiko Seki
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
pancreatic ductal adenocarcinoma
microRNA
tumor-suppressor
<i>miR-30c-5p</i>
<i>miR-30c-2-3p</i>
<i>TOP2A</i>
Online Access:https://www.mdpi.com/2072-6694/12/10/2731

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https://www.mdpi.com/2072-6694/12/10/2731

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