Proteomic Analysis of KCNK3 Loss of Expression Identified Dysregulated Pathways in Pulmonary Vascular Cells

Proteomic Analysis of KCNK3 Loss of Expression Identified Dysregulated Pathways in Pulmonary Vascular Cells

The physiopathology of pulmonary arterial hypertension (PAH) is characterized by pulmonary artery smooth muscle cell (PASMC) and endothelial cell (PAEC) dysfunction, contributing to pulmonary arterial obstruction and PAH progression. KCNK3 loss of function mutations are responsible for the first cha...

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Bibliographic Details
Main Authors: Hélène Le Ribeuz, Florent Dumont, Guillaume Ruellou, Mélanie Lambert, Thierry Balliau, Marceau Quatredeniers, Barbara Girerd, Sylvia Cohen-Kaminsky, Olaf Mercier, Stéphanie Yen-Nicolaÿ, Marc Humbert, David Montani, Véronique Capuano, Fabrice Antigny
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
PAH
potassium channel
proteomic
Online Access:https://www.mdpi.com/1422-0067/21/19/7400

Internet

https://www.mdpi.com/1422-0067/21/19/7400

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