TTP-like syndrome: novel concept and molecular pathogenesis of endotheliopathy-associated vascular microthrombotic disease

TTP-like syndrome: novel concept and molecular pathogenesis of endotheliopathy-associated vascular microthrombotic disease

Abstract TTP is characterized by microangiopathic hemolytic anemia and thrombocytopenia associated with brain and kidney dysfunction. It occurs due to ADAMTS13 deficiency. TTP-like syndrome occurs in critically ill patients with the similar hematologic changes and additional organ dysfunction syndro...

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Bibliographic Details
Main Author: Jae C. Chang
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Thrombosis Journal
Subjects:
ADAMTS13
Complement
Disseminated intravascular coagulation (DIC)
Disseminated intravascular microthrombosis (DIT)
Endotheliopathy
Microthrombogenesis
Online Access:http://link.springer.com/article/10.1186/s12959-018-0174-4

Internet

http://link.springer.com/article/10.1186/s12959-018-0174-4

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