Polyoxygenated Steroids from the Octocoral Leptogorgia punicea and in Vitro Evaluation of Their Cytotoxic Activity

Polyoxygenated Steroids from the Octocoral Leptogorgia punicea and in Vitro Evaluation of Their Cytotoxic Activity

Five new polyoxygenated marine steroids—punicinols A–E (1–5)—were isolated from the gorgonian Leptogorgia punicea and characterized by spectroscopic methods (IR, MS, 1H, 13C and 2-D NMR). The five compounds induced in vitro cytotoxic effects against lung cancer A549 cells, while punicinols A and B w...

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Bibliographic Details
Main Authors: Maria Izabel G. Moritz, Lucas Lourenço Marostica, Éverson M. Bianco, Maria Tereza R. Almeida, João L. Carraro, Gabriela M. Cabrera, Jorge A. Palermo, Cláudia M. O. Simões, Eloir P. Schenkel
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Marine Drugs
Subjects:
Leptogorgia punicea
octocoral
polyoxygenated steroids
cytotoxic effects
A549 cells
lung cancer cells
Online Access:http://www.mdpi.com/1660-3397/12/12/5864

Internet

http://www.mdpi.com/1660-3397/12/12/5864

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