Modulation of HIV-1 infectivity and cyclophilin A-dependence by Gag sequence and target cell type
<p>Abstract</p> <p>Background</p> <p>HIV-1 Gag proteins are essential for virion assembly and viral replication in newly infected cells. Gag proteins are also strong determinants of viral infectivity; immune escape mutations in the Gag capsid (CA) protein can markedly r...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-03-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/6/1/21 |