Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction

<p>Abstract</p> <p>Background</p> <p>In guinea pigs, we have previously demonstrated that the contribution of Rho-kinase to airway responsiveness <it>in vivo </it>and <it>ex vivo </it>is enhanced after active sensitization with ovalbumin (OA). Us...

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Bibliographic Details
Main Authors: Zaagsma Johan, Zuidhof Annet B, Bos I Sophie T, Schaafsma Dedmer, Meurs Herman
Format: Article
Language:English
Published: BMC 2006-09-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/7/1/121