JAK/STAT-Activating Genomic Alterations Are a Hallmark of T-PLL

JAK/STAT-Activating Genomic Alterations Are a Hallmark of T-PLL

<b> </b>T-cell prolymphocytic leukemia (T-PLL) is a rare and poor-prognostic mature T-cell leukemia. Recent studies detected genomic aberrations affecting <i>JAK </i>and <i>STAT </i>genes in T-PLL. Due to the limited number of primary patient samples available, ge...

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Bibliographic Details
Main Authors: Linus Wahnschaffe, Till Braun, Sanna Timonen, Anil K. Giri, Alexandra Schrader, Prerana Wagle, Henrikki Almusa, Patricia Johansson, Dorine Bellanger, Cristina López, Claudia Haferlach, Marc-Henri Stern, Jan Dürig, Reiner Siebert, Satu Mustjoki, Tero Aittokallio, Marco Herling
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
jak
stat
t-pll
t-cell leukemia
meta-analysis
stat5b signaling
Online Access:https://www.mdpi.com/2072-6694/11/12/1833

Internet

https://www.mdpi.com/2072-6694/11/12/1833

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