IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma

IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma

<p>Abstract</p> <p>Background</p> <p>Ocular hypertension is a major risk factor for glaucoma, a neurodegenerative disease characterized by an irreversible decrease in ganglion cells and their axons. Macroglial and microglial cells appear to play an important role in the...

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Bibliographic Details
Main Authors: Gallego Beatriz I, Salazar Juan J, de Hoz Rosa, Rojas Blanca, Ramírez Ana I, Salinas-Navarro Manuel, Ortín-Martínez Arturo, Valiente-Soriano Francisco J, Avilés-Trigueros Marcelino, Villegas-Perez Maria P, Vidal-Sanz Manuel, Triviño Alberto, Ramírez Jose M
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Journal of Neuroinflammation
Subjects:
Experimental glaucoma
Mice
Microglia
Astrocytes
Müller cell
Retina
GFAP
MHC-II
Online Access:http://www.jneuroinflammation.com/content/9/1/92

Internet

http://www.jneuroinflammation.com/content/9/1/92

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