A Phase I Study of High-Dose Calcitriol in Combination with Temozolomide for Patients with Metastatic Melanoma
Background: Temozolomide is efficacious as an oral alternative for patients with metastatic melanoma (MM). Calcitriol has anti-proliferative properties and vitamin D receptor (VDR) polymorphisms are associated with alterations in melanoma susceptibility and progression. Methods: Tem 150 mg/m2 was ad...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-10-01
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Series: | Journal of Personalized Medicine |
Subjects: | |
Online Access: | http://www.mdpi.com/2075-4426/4/4/448 |