Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension

Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension

Abstract Background Pulmonary hypertension (PH) is a progressive disease leading to death ultimately. Our recently published data demonstrated that inhibiting dipeptidyl peptidase IV (DPP-4) alleviated pulmonary vascular remodeling in experimental PH. However, whether glucagon-like peptide-1 (GLP-1)...

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Bibliographic Details
Main Authors: Jingjing Wang, Min Yu, Jian Xu, Yusheng Cheng, Xiang Li, Guihong Wei, Hong Wang, Hui Kong, Weiping Xie
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Biomedical Science
Subjects:
DPP-4i
GLP-1
Pulmonary vascular remodeling
Online Access:http://link.springer.com/article/10.1186/s12929-019-0496-y

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http://link.springer.com/article/10.1186/s12929-019-0496-y

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