The Role of Substance P in Secondary Pathophysiology after Traumatic Brain Injury

The Role of Substance P in Secondary Pathophysiology after Traumatic Brain Injury

It has recently been shown that substance P (SP) plays a major role in the secondary injury process following traumatic brain injury (TBI), particularly with respect to neuroinflammation, increased blood–brain barrier (BBB) permeability, and edema formation. Edema formation is associated with the de...

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Bibliographic Details
Main Authors: Robert Vink, Levon Gabrielian, Emma Thornton
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Neurology
Subjects:
substance P
traumatic brain injury
edema
intracranial pressure
brain oxygenation
sheep model
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00304/full

Internet

http://journal.frontiersin.org/article/10.3389/fneur.2017.00304/full

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