Differential expression of interferon responsive genes in rodent models of transmissible spongiform encephalopathy disease

<p>Abstract</p> <p>Background</p> <p>The pathological hallmarks of transmissible spongiform encephalopathy (TSE) diseases are the deposition of a misfolded form of a host-encoded protein (PrP<sup>res</sup>), marked astrocytosis, microglial activation and spo...

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Bibliographic Details
Main Authors: Lazar Jozef, LeMaistre Jillian, Simon Sharon LR, Parchaliuk Debra, Stobart Michael J, Rubenstein Richard, Knox J David
Format: Article
Language:English
Published: BMC 2007-03-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/2/1/5