FoxP3+ regulatory T cells determine disease severity in rodent models of inflammatory neuropathies.

Inflammatory neuropathies represent disabling human autoimmune disorders with considerable disease variability. Animal models provide insights into defined aspects of their disease pathogenesis. Forkhead box P3 (FoxP3)+ regulatory T lymphocytes (Treg) are anti-inflammatory cells that maintain immune...

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Bibliographic Details
Main Authors: Gerd Meyer zu Hörste, Steffen Cordes, Anne K Mausberg, Alla L Zozulya, Carsten Wessig, Tim Sparwasser, Christian Mathys, Heinz Wiendl, Hans-Peter Hartung, Bernd C Kieseier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0108756