Spontaneous shaker rat mutant – a new model for X-linked tremor/ataxia

Spontaneous shaker rat mutant – a new model for X-linked tremor/ataxia

The shaker rat is an X-linked recessive spontaneous model of progressive Purkinje cell (PC) degeneration exhibiting a shaking ataxia and wide stance. Generation of Wistar Furth (WF)/Brown Norwegian (BN) F1 hybrids and genetic mapping of F2 sib-sib offspring using polymorphic markers narrowed the can...

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Bibliographic Details
Main Authors: Karla P. Figueroa, Sharan Paul, Tito Calì, Raffaele Lopreiato, Sukanya Karan, Martina Frizzarin, Darren Ames, Ginevra Zanni, Marisa Brini, Warunee Dansithong, Brett Milash, Daniel R. Scoles, Ernesto Carafoli, Stefan M. Pulst
Format: Article
Language:English
Published: The Company of Biologists 2016-05-01
Series:Disease Models & Mechanisms
Subjects:
Ataxia
X-linked
shaker
PMCA3
Atp2b3
Online Access:http://dmm.biologists.org/content/9/5/553

Internet

http://dmm.biologists.org/content/9/5/553

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