Consistent tumorigenesis with self-assembled hydrogels enables high-powered murine cancer studies

Grosskopf et al. report the development of a tumor inoculation method using self-assembled alginate hydrogels containing different tumorigenic molecules to reproducibly generate tumors in a subcutaneous murine tumor model. They show the impact of this improved model on the reduction of cohort size a...

Full description

Bibliographic Details
Main Authors: Abigail K. Grosskopf, Santiago Correa, Julie Baillet, Caitlin L. Maikawa, Emily C. Gale, Ryanne A. Brown, Eric A. Appel
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02500-8