Tau and Membranes: Interactions That Promote Folding and Condensation

Tau and Membranes: Interactions That Promote Folding and Condensation

Tau misfolding and assembly is linked to a number of neurodegenerative diseases collectively described as tauopathies, including Alzheimer’s disease (AD) and Parkinson’s disease. Anionic cellular membranes, such as the cytosolic leaflet of the plasma membrane, are sites that concentrate and neutrali...

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Bibliographic Details
Main Authors: Chad A. Sallaberry, Barbie J. Voss, Jaroslaw Majewski, Jacek Biernat, Eckhard Mandelkow, Eva Y. Chi, Crystal M. Vander Zanden
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
tau
membrane
condensation
polyanionic surface
fibrils
phase separation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.725241/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.725241/full

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