Interaction of HSD11B1 and H6PD polymorphisms in subjects with type 2 diabetes are protective factors against obesity: a cross-sectional study

Interaction of HSD11B1 and H6PD polymorphisms in subjects with type 2 diabetes are protective factors against obesity: a cross-sectional study

Abstract Background The enzyme 11-beta hydroxysteroid dehydrogenase type 1 (HSD11B1) converts inactive cortisone to active cortisol in a process mediated by the enzyme hexose-6-phosphate dehydrogenase (H6PD). The generation of cortisol from this reaction may increase intra-abdominal cortisol levels...

Full description

Bibliographic Details
Main Authors: Marcio F. Chedid, Filipe V. do Nascimento, Fernanda S. de Oliveira, Bianca M. de Souza, Cleber R. P. Kruel, Richard R. Gurski, Luis H. Canani, Daisy Crispim, Fernando Gerchman
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Gene expression
Cortisol
11-beta hydroxysteroid dehydrogenase type 1
Hexose-6-phosphate dehydrogenase
Visceral
Adipose tissue
Online Access:http://link.springer.com/article/10.1186/s13098-019-0474-2

Internet

http://link.springer.com/article/10.1186/s13098-019-0474-2

Similar Items