Extended role of necrotic cell death after hypoxia–ischemia-induced neurodegeneration in the neonatal rat

The relative contribution of apoptosis and necrosis after neonatal hypoxia–ischemia (HI) is still a matter of debate. Here we determined the time course of necrotic cell death after neonatal HI and its relationship to caspase-3 activation and apoptotic cell death. Necrosis was evaluated by intracere...

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Bibliographic Details
Main Authors: Silvia Carloni, Andrea Carnevali, Mauro Cimino, Walter Balduini
Format: Article
Language:English
Published: Elsevier 2007-09-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107001155