Prospects for a nonliving vaccine against Schistosomiasis based on cell-mediated immune resistance mechanisms
We have designed a vaccine model based on induction of cell-mediated immunity and shown that it protects mice against Schistosoma mansoni infection. Mice are immunized by intradermal injection with schistosome antigens plus BCG. Resistance is dependent on the route of antigen presentation and the ad...
Main Authors: | Stephanie L. James, Edward J. Pearce, Alan Sher |
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Format: | Article |
Language: | English |
Published: |
Instituto Oswaldo Cruz, Ministério da Saúde
1987-01-01
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Series: | Memórias do Instituto Oswaldo Cruz. |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000800020 |
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