Prospects for a nonliving vaccine against Schistosomiasis based on cell-mediated immune resistance mechanisms

by Stephanie L. James, Edward J. Pearce, Alan Sher
Published 1987-01-01

TGF-beta signaling controls embryo development in the parasitic flatworm Schistosoma mansoni.

by Tori C Freitas, Euihye Jung, Edward J Pearce
Published 2007-04-01

Metabolic Control of Dendritic Cell Activation and Function: Recent Advances and Clinical Implications

by Bart eEverts, Bart eEverts, Edward J Pearce
Published 2014-05-01

Cell death and reproductive regression in female Schistosoma mansoni.

by Sarah E Galanti, Stanley Ching-Cheng Huang, Edward J Pearce
Published 2012-01-01

MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells

by Tanya Kapoor, Mauro Corrado, Erika L. Pearce, Edward J. Pearce, Rudolf Grosschedl
Published 2020-12-01

Transposon-mediated chromosomal integration of transgenes in the parasitic nematode Strongyloides ratti and establishment of stable transgenic lines.

by Hongguang Shao, Xinshe Li, Thomas J Nolan, Holman C Massey, Edward J Pearce, James B Lok
Published 2012-01-01

IL-10R blockade during chronic schistosomiasis mansoni results in the loss of B cells from the liver and the development of severe pulmonary disease.

by Keke C Fairfax, Eyal Amiel, Irah L King, Tori C Freitas, Markus Mohrs, Edward J Pearce
Published 2012-01-01

Fatty acid oxidation is essential for egg production by the parasitic flatworm Schistosoma mansoni.

by Stanley Ching-Cheng Huang, Tori C Freitas, Eyal Amiel, Bart Everts, Erika L Pearce, James B Lok, Edward J Pearce
Published 2012-01-01

Ly6Chi monocyte recruitment is responsible for Th2 associated host-protective macrophage accumulation in liver inflammation due to schistosomiasis.

by Marcia Nascimento, Stanley C Huang, Amber Smith, Bart Everts, Wing Lam, Elizabeth Bassity, Emmanuel L Gautier, Gwendalyn J Randolph, Edward J Pearce
Published 2014-08-01

Discovery of anthelmintic drug targets and drugs using chokepoints in nematode metabolic pathways.

by Christina M Taylor, Qi Wang, Bruce A Rosa, Stanley Ching-Cheng Huang, Kerrie Powell, Tim Schedl, Edward J Pearce, Sahar Abubucker, Makedonka Mitreva
Published 2013-01-01

Suppression of mRNAs encoding tegument tetraspanins from Schistosoma mansoni results in impaired tegument turnover.

by Mai H Tran, Tori C Freitas, Leanne Cooper, Soraya Gaze, Michelle L Gatton, Malcolm K Jones, Erica Lovas, Edward J Pearce, Alex Loukas
Published 2010-04-01

Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype

by Diana Cortes-Selva, Andrew F. Elvington, Andrew F. Elvington, Andrew Ready, Bartek Rajwa, Edward J. Pearce, Gwendalyn J. Randolph, Keke C. Fairfax, Keke C. Fairfax
Published 2018-11-01

IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals

by Michal A. Stanczak, David E. Sanin, Petya Apostolova, Gabriele Nerz, Dimitrios Lampaki, Maike Hofmann, Daniel Steinmann, Marvin Krohn-Grimberghe, Robert Thimme, Gerhard Mittler, Cornelius F. Waller, Edward J. Pearce, Erika L. Pearce
Published 2021-04-01

TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control TH2-Mediated Immunopathology.

by Yashaswini Kannan, Jimena Perez-Lloret, Yanda Li, Lewis J Entwistle, Hania Khoury, Stamatia Papoutsopoulou, Radma Mahmood, Nuha R Mansour, Stanley Ching-Cheng Huang, Edward J Pearce, Luiz Pedro S de Carvalho, Steven C Ley, Mark S Wilson
Published 2016-08-01

The Transcriptional Repressor Polycomb Group Factor 6, PCGF6, Negatively Regulates Dendritic Cell Activation and Promotes Quiescence

by Giselle M. Boukhaled, Brendan Cordeiro, Genevieve Deblois, Vassil Dimitrov, Swneke D. Bailey, Thomas Holowka, Anisa Domi, Hannah Guak, Huai-Hsuan Clare Chiu, Bart Everts, Edward J. Pearce, Mathieu Lupien, John H. White, Connie M. Krawczyk
Published 2016-08-01

Triacylglycerol synthesis enhances macrophage inflammatory function

by Angela Castoldi, Lauar B. Monteiro, Nikki van Teijlingen Bakker, David E. Sanin, Nisha Rana, Mauro Corrado, Alanna M. Cameron, Fabian Hässler, Mai Matsushita, George Caputa, Ramon I. Klein Geltink, Jörg Büscher, Joy Edwards-Hicks, Erika L. Pearce, Edward J. Pearce
Published 2020-08-01

IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection.

by Marcela Montes de Oca, Fabian de Labastida Rivera, Clay Winterford, Teija C M Frame, Susanna S Ng, Fiona H Amante, Chelsea L Edwards, Luzia Bukali, Yulin Wang, Jude E Uzonna, Rachel D Kuns, Ping Zhang, Agnieszka Kabat, Ramon I Klein Geltink, Edward J Pearce, Geoffrey R Hill, Christian R Engwerda
Published 2020-10-01

Acetate Promotes T Cell Effector Function during Glucose Restriction

by Jing Qiu, Matteo Villa, David E. Sanin, Michael D. Buck, David O’Sullivan, Reagan Ching, Mai Matsushita, Katarzyna M. Grzes, Frances Winkler, Chih-Hao Chang, Jonathan D. Curtis, Ryan L. Kyle, Nikki Van Teijlingen Bakker, Mauro Corrado, Fabian Haessler, Francesca Alfei, Joy Edwards-Hicks, Leonard B. Maggi, Jr., Dietmar Zehn, Takeshi Egawa, Bertram Bengsch, Ramon I. Klein Geltink, Thomas Jenuwein, Edward J. Pearce, Erika L. Pearce
Published 2019-05-01