Functional Avidity: A Measure to Predict the Efficacy of Effector T Cells?

by Selena Viganò, Daniel T. Utzschneider, Matthieu Perreau, Giuseppe Pantaleo, Dietmar Zehn, Alexandre Harari
Published 2012-01-01

Resistance to TGFβ suppression and improved anti-tumor responses in CD8+ T cells lacking PTPN22

by Rebecca J. Brownlie, Celine Garcia, Mate Ravasz, Dietmar Zehn, Robert J. Salmond, Rose Zamoyska
Published 2017-11-01

Tailoring the resolution of single-cell RNA sequencing for primary cytotoxic T cells

by Kristiyan Kanev, Patrick Roelli, Ming Wu, Christine Wurmser, Mauro Delorenzi, Michael W. Pfaffl, Dietmar Zehn
Published 2021-01-01

A Minimum Epitope Overlap between Infections Strongly Narrows the Emerging T Cell Repertoire

by Susanne G. Oberle, Layane Hanna-El-Daher, Vijaykumar Chennupati, Sarah Enouz, Stefanie Scherer, Martin Prlic, Dietmar Zehn
Published 2016-10-01

Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells

by Veronika Horkova, Ales Drobek, Daniel Mueller, Celine Gubser, Veronika Niederlova, Lena Wyss, Carolyn G. King, Dietmar Zehn, Ondrej Stepanek
Published 2020-02-01

Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts.

by Karin Schaeuble, Hélène Cannelle, Stéphanie Favre, Hsin-Ying Huang, Susanne G Oberle, Daniel E Speiser, Dietmar Zehn, Sanjiv A Luther
Published 2019-07-01

Loss of the orphan nuclear receptor NR2F6 enhances CD8+ T-cell memory via IFN-γ

by Bojana Jakic, William J. Olson, Kerstin Siegmund, Victoria Klepsch, Janine Kimpel, Verena Labi, Dietmar Zehn, Gottfried Baier, Natascha Hermann-Kleiter
Published 2021-02-01

TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation

by Dominik Wieland, Janine Kemming, Anita Schuch, Florian Emmerich, Percy Knolle, Christoph Neumann-Haefelin, Werner Held, Dietmar Zehn, Maike Hofmann, Robert Thimme
Published 2017-05-01

Bystander-Activated Memory CD8 T Cells Control Early Pathogen Load in an Innate-like, NKG2D-Dependent Manner

by Talyn Chu, Aaron J. Tyznik, Sarah Roepke, Amy M. Berkley, Amanda Woodward-Davis, Laura Pattacini, Michael J. Bevan, Dietmar Zehn, Martin Prlic
Published 2013-03-01

Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo

by Giorgia Rota, Charlène Niogret, Anh Thu Dang, Cristina Ramon Barros, Nicolas Pierre Fonta, Francesca Alfei, Leonor Morgado, Dietmar Zehn, Walter Birchmeier, Eric Vivier, Greta Guarda
Published 2018-04-01

NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions

by Kristina Ludigs, Camilla Jandus, Daniel T. Utzschneider, Francesco Staehli, Stéphanie Bessoles, Anh Thu Dang, Giorgia Rota, Wilson Castro, Dietmar Zehn, Eric Vivier, Werner Held, Pedro Romero, Greta Guarda
Published 2016-02-01

Lymphatic endothelial cells prime naïve CD8+ T cells into memory cells under steady-state conditions

by Efthymia Vokali, Shann S. Yu, Sachiko Hirosue, Marcela Rinçon-Restrepo, Fernanda V. Duraes, Stefanie Scherer, Patricia Corthésy-Henrioud, Witold W. Kilarski, Anna Mondino, Dietmar Zehn, Stéphanie Hugues, Melody A. Swartz
Published 2020-01-01

PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells

by Markus Flosbach, Susanne G. Oberle, Stefanie Scherer, Jana Zecha, Madlaina von Hoesslin, Florian Wiede, Vijaykumar Chennupati, Jolie G. Cullen, Markus List, Josch K. Pauling, Jan Baumbach, Bernhard Kuster, Tony Tiganis, Dietmar Zehn
Published 2020-07-01

Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner

by Lianjun Zhang, Benjamin O. Tschumi, Isabel C. Lopez-Mejia, Susanne G. Oberle, Marten Meyer, Guerric Samson, Markus A. Rüegg, Michael N. Hall, Lluis Fajas, Dietmar Zehn, Jean-Pierre Mach, Alena Donda, Pedro Romero
Published 2016-02-01

Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide.

by Stefanie Siegert, Hsin-Ying Huang, Chen-Ying Yang, Leonardo Scarpellino, Lucie Carrie, Sarah Essex, Peter J Nelson, Matthias Heikenwalder, Hans Acha-Orbea, Christopher D Buckley, Benjamin J Marsland, Dietmar Zehn, Sanjiv A Luther
Published 2011-01-01

Exacerbated Leishmaniasis Caused by a Viral Endosymbiont can be Prevented by Immunization with Its Viral Capsid.

by Patrik Castiglioni, Mary-Anne Hartley, Matteo Rossi, Florence Prevel, Chantal Desponds, Daniel T Utzschneider, Remzi-Onur Eren, Haroun Zangger, Livia Brunner, Nicolas Collin, Dietmar Zehn, F Matthew Kuhlmann, Stephen M Beverley, Nicolas Fasel, Catherine Ronet
Published 2017-01-01

Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells.

by Dennis J Wu, Wenbo Zhou, Sarah Enouz, Valeria Orrú, Stephanie M Stanford, Christian J Maine, Novella Rapini, Kristy Sawatzke, Isaac Engel, Edoardo Fiorillo, Linda A Sherman, Mitch Kronenberg, Dietmar Zehn, Erik Peterson, Nunzio Bottini
Published 2014-01-01

SARS‐CoV‐2 infections in cancer outpatients—Most infected patients are asymptomatic carriers without impact on chemotherapy

by Louisa Hempel, Armin Piehler, Michael W. Pfaffl, Jakob Molnar, Benedikt Kirchner, Sebastian Robert, Julia Veloso, Beate Gandorfer, Zeljka Trepotec, Stefanie Mederle, Sabine Keim, Valeria Milani, Florian Ebner, Katrin Schweneker, Bastian Fleischmann, Axel Kleespies, Josef Scheiber, Dirk Hempel, Dietmar Zehn
Published 2020-11-01

Siglec-H-Deficient Mice Show Enhanced Type I IFN Responses, but Do Not Develop Autoimmunity After Influenza or LCMV Infections

by Nadine Szumilas, Odilia B. J. Corneth, Christian H. K. Lehmann, Christian H. K. Lehmann, Christian H. K. Lehmann, Heike Schmitt, Svenia Cunz, Jolie G. Cullen, Talyn Chu, Anita Marosan, Attila Mócsai, Vladimir Benes, Dietmar Zehn, Diana Dudziak, Diana Dudziak, Diana Dudziak, Rudi W. Hendriks, Lars Nitschke, Lars Nitschke
Published 2021-08-01

Acetate Promotes T Cell Effector Function during Glucose Restriction

by Jing Qiu, Matteo Villa, David E. Sanin, Michael D. Buck, David O’Sullivan, Reagan Ching, Mai Matsushita, Katarzyna M. Grzes, Frances Winkler, Chih-Hao Chang, Jonathan D. Curtis, Ryan L. Kyle, Nikki Van Teijlingen Bakker, Mauro Corrado, Fabian Haessler, Francesca Alfei, Joy Edwards-Hicks, Leonard B. Maggi, Jr., Dietmar Zehn, Takeshi Egawa, Bertram Bengsch, Ramon I. Klein Geltink, Thomas Jenuwein, Edward J. Pearce, Erika L. Pearce
Published 2019-05-01