Establishment and Characterization of a Functionally Competent Type 2 Conventional Dendritic Cell Line

by Matteo Pigni, Devika Ashok, Mathias Stevanin, Hans Acha-Orbea
Published 2018-08-01

Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections

by Eleonora Ciarlo, Tytti Heinonen, Jérôme Lugrin, Hans Acha-Orbea, Didier Le Roy, Johan Auwerx, Thierry Roger
Published 2017-06-01

IL10- and IL35-Secreting MutuDC Lines Act in Cooperation to Inhibit Memory T Cell Activation Through LAG-3 Expression

by Marianna M. Koga, Adrien Engel, Matteo Pigni, Christine Lavanchy, Mathias Stevanin, Vanessa Laversenne, Bernard L. Schneider, Bernard L. Schneider, Hans Acha-Orbea
Published 2021-02-01

NCoR1 is a master repressor of the tolerogenic program in dendritic cells

by Abdul Ahad, Mathias Stevanin, Shuchi Smita, Gyan P. Mishra, Dheerendra Gupta, Sebastian M. Waszak, Bhawna Gupta, Hans Acha-Orbea, Sunil K. Raghav
Published 2017-10-01

Distinct pathophysiological cytokine profiles for discrimination between autoimmune pancreatitis, chronic pancreatitis, and pancreatic ductal adenocarcinoma

by Sahar Ghassem-Zadeh, Matthias M. Gaida, Szilard Szanyi, Hans Acha-Orbea, Jean-Louis Frossard, Ulf Hinz, Thilo Hackert, Oliver Strobel, Klaus Felix
Published 2017-06-01

Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth

by Teruo Kusano, Driss Ehirchiou, Tomohiro Matsumura, Veronique Chobaz, Sonia Nasi, Mariela Castelblanco, Alexander So, Christine Lavanchy, Hans Acha-Orbea, Takeshi Nishino, Ken Okamoto, Nathalie Busso
Published 2019-10-01

Dendritic Cells Cause Bone Lesions in a New Mouse Model of Histiocytosis.

by Frédéric Grosjean, Sonia Nasi, Pascal Schneider, Véronique Chobaz, Alexandra Liu, Vanessa Mordasini, Kristell Moullec, Paolo Vezzoni, Christine Lavanchy, Nathalie Busso, Hans Acha-Orbea, Driss Ehirchiou
Published 2015-01-01

NCoR1: Putting the Brakes on the Dendritic Cell Immune Tolerance

by Abdul Ahad, Mathias Stevanin, Shuchi Smita, Gyan Prakash Mishra, Dheerendra Gupta, Sebastian Waszak, Uday Aditya Sarkar, Soumen Basak, Bhawna Gupta, Hans Acha-Orbea, Sunil Kumar Raghav
Published 2019-09-01

Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis.

by Christoph Thelemann, Remzi Onur Eren, Manuel Coutaz, Jennifer Brasseit, Hanifa Bouzourene, Muriel Rosa, Anais Duval, Christine Lavanchy, Vanessa Mack, Christoph Mueller, Walter Reith, Hans Acha-Orbea
Published 2014-01-01

Sirtuin 2 Deficiency Increases Bacterial Phagocytosis by Macrophages and Protects from Chronic Staphylococcal Infection

by Eleonora Ciarlo, Tytti Heinonen, Charlotte Théroude, Jacobus Herderschee, Matteo Mombelli, Jérôme Lugrin, Marc Pfefferlé, Beatrice Tyrrell, Sarah Lensch, Hans Acha-Orbea, Didier Le Roy, Johan Auwerx, Thierry Roger
Published 2017-08-01

Novel Autoantibody Signatures in Sera of Patients with Pancreatic Cancer, Chronic Pancreatitis and Autoimmune Pancreatitis: A Protein Microarray Profiling Approach

by Sahar Ghassem-Zadeh, Katrin Hufnagel, Andrea Bauer, Jean-Louis Frossard, Masaru Yoshida, Hiromu Kutsumi, Hans Acha-Orbea, Matthias Neulinger-Muñoz, Johannes Vey, Christoph Eckert, Oliver Strobel, Jörg D. Hoheisel, Klaus Felix
Published 2020-03-01

Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo.

by Silvia A Fuertes Marraco, Clare L Scott, Philippe Bouillet, Annette Ives, Slavica Masina, David Vremec, Elisa S Jansen, Lorraine A O'Reilly, Pascal Schneider, Nicolas Fasel, Ken Shortman, Andreas Strasser, Hans Acha-Orbea
Published 2011-01-01

Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide.

by Stefanie Siegert, Hsin-Ying Huang, Chen-Ying Yang, Leonardo Scarpellino, Lucie Carrie, Sarah Essex, Peter J Nelson, Matthias Heikenwalder, Hans Acha-Orbea, Christopher D Buckley, Benjamin J Marsland, Dietmar Zehn, Sanjiv A Luther
Published 2011-01-01

Importance of EMT Factor ZEB1 in cDC1 “MutuDC Line” Mediated Induction of Th1 Immune Response

by Shuchi Smita, Shuchi Smita, Abdul Ahad, Abdul Ahad, Arup Ghosh, Arup Ghosh, Viplov K. Biswas, Viplov K. Biswas, Marianna M. Koga, Bhawna Gupta, Hans Acha-Orbea, Sunil K. Raghav, Sunil K. Raghav, Sunil K. Raghav
Published 2018-11-01