The essentials of developmental apoptosis [version 1; peer review: 3 approved]

by Anne K. Voss, Andreas Strasser
Published 2020-02-01

Distinct target genes and effector processes appear to be critical for p53-activated responses to acute DNA damage versus p53-mediated tumour suppression

by Liz J Valente, Andreas Strasser
Published 2013-06-01

Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner

by Rui Liu, Ashleigh King, Ashleigh King, Philippe Bouillet, Philippe Bouillet, David M. Tarlinton, Andreas Strasser, Andreas Strasser, Jörg Heierhorst, Jörg Heierhorst
Published 2018-03-01

Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics.

by Mark S Cragg, Junya Kuroda, Hamsa Puthalakath, David C S Huang, Andreas Strasser
Published 2007-10-01

Loss of a Single Mcl-1 Allele Inhibits MYC-Driven Lymphomagenesis by Sensitizing Pro-B Cells to Apoptosis

by Stephanie Grabow, Alex R.D. Delbridge, Brandon J. Aubrey, Cassandra J. Vandenberg, Andreas Strasser
Published 2016-03-01

Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms.

by Ashleigh King, Lingli Li, David M Wong, Rui Liu, Rebecca Bamford, Andreas Strasser, David M Tarlinton, Jörg Heierhorst
Published 2017-09-01

DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice

by Eleonora Ottina, Victor Peperzak, Katia Schoeler, Emma Carrington, Roswitha Sgonc, Marc Pellegrini, Simon Preston, Marco J. Herold, Andreas Strasser, Andreas Villunger
Published 2017-10-01

p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa

by Liz J. Valente, Daniel H.D. Gray, Ewa M. Michalak, Josefina Pinon-Hofbauer, Alex Egle, Clare L. Scott, Ana Janic, Andreas Strasser
Published 2013-05-01

Bim expression in endothelial cells and pericytes is essential for regression of the fetal ocular vasculature.

by Shoujian Wang, Ismail S Zaitoun, Ryan P Johnson, Nasim Jamali, Zafer Gurel, Catherine M Wintheiser, Andreas Strasser, Volkhard Lindner, Nader Sheibani, Christine M Sorenson
Published 2017-01-01

An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo

by Brandon J. Aubrey, Gemma L. Kelly, Andrew J. Kueh, Margs S. Brennan, Liam O’Connor, Liz Milla, Stephen Wilcox, Lin Tai, Andreas Strasser, Marco J. Herold
Published 2015-03-01

Background Concentrations of Cultivable, Mesophilic Bacteria and Dust Particles in the Air in Urban, Rural and Mountain Regions

by Doris Haas, Angela Kriso, Theresa Fritz, Herbert Galler, Juliana Habib, Mihaela Ilieva, Michael Kropsch, Petra Ofner-Kopeinig, Martin Stonitsch, Andreas Strasser, Eduard Zentner, Franz F. Reinthaler
Published 2020-12-01

The Transcription Factor ASCIZ and Its Target DYNLL1 Are Essential for the Development and Expansion of MYC-Driven B Cell Lymphoma

by David M. Wong, Lingli Li, Sabine Jurado, Ashleigh King, Rebecca Bamford, Meaghan Wall, Mannu K. Walia, Gemma L. Kelly, Carl R. Walkley, David M. Tarlinton, Andreas Strasser, Jörg Heierhorst
Published 2016-02-01

Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells

by Liz J. Valente, Brandon J. Aubrey, Marco J. Herold, Gemma L. Kelly, Lina Happo, Clare L. Scott, Andrea Newbold, Ricky W. Johnstone, David C.S. Huang, Lyubomir T. Vassilev, Andreas Strasser
Published 2016-03-01

Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo.

by Silvia A Fuertes Marraco, Clare L Scott, Philippe Bouillet, Annette Ives, Slavica Masina, David Vremec, Elisa S Jansen, Lorraine A O'Reilly, Pascal Schneider, Nicolas Fasel, Ken Shortman, Andreas Strasser, Hans Acha-Orbea
Published 2011-01-01

XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation

by Monica Yabal, Nicole Müller, Heiko Adler, Nathalie Knies, Christina J. Groß, Rune Busk Damgaard, Hirokazu Kanegane, Marc Ringelhan, Thomas Kaufmann, Mathias Heikenwälder, Andreas Strasser, Olaf Groß, Jürgen Ruland, Christian Peschel, Mads Gyrd-Hansen, Philipp J. Jost
Published 2014-06-01

IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and Mitochondrial Homeostasis

by Michael Sze Yuan Low, Erica J. Brodie, Pasquale L. Fedele, Yang Liao, George Grigoriadis, Andreas Strasser, Axel Kallies, Simon N. Willis, Julie Tellier, Wei Shi, Sarah Gabriel, Kristy O’Donnell, Catherine Pitt, Stephen L. Nutt, David Tarlinton
Published 2019-11-01

Subtle Changes in the Levels of BCL-2 Proteins Cause Severe Craniofacial Abnormalities

by Stephanie Grabow, Andrew J. Kueh, Francine Ke, Hannah K. Vanyai, Bilal N. Sheikh, Michael A. Dengler, William Chiang, Samantha Eccles, Ian M. Smyth, Lynelle K. Jones, Frederic J. de Sauvage, Mark Scott, Lachlan Whitehead, Anne K. Voss, Andreas Strasser
Published 2018-09-01

LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L

by Lucia Taraborrelli, Nieves Peltzer, Antonella Montinaro, Sebastian Kupka, Eva Rieser, Torsten Hartwig, Aida Sarr, Maurice Darding, Peter Draber, Tobias L. Haas, Ayse Akarca, Teresa Marafioti, Manolis Pasparakis, John Bertin, Peter J. Gough, Philippe Bouillet, Andreas Strasser, Martin Leverkus, John Silke, Henning Walczak
Published 2018-09-01

Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis

by Charis E. Teh, Najoua Lalaoui, Reema Jain, Antonia N. Policheni, Melanie Heinlein, Silvia Alvarez-Diaz, Julie M. Sheridan, Eva Rieser, Stefanie Deuser, Maurice Darding, Hui-Fern Koay, Yifang Hu, Fiona Kupresanin, Lorraine A. O’Reilly, Dale I. Godfrey, Gordon K. Smyth, Philippe Bouillet, Andreas Strasser, Henning Walczak, John Silke, Daniel H. D. Gray
Published 2016-11-01

Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects

by Alex R.D. Delbridge, Andrew J. Kueh, Francine Ke, Natasha M. Zamudio, Farrah El-Saafin, Natasha Jansz, Gao-Yuan Wang, Megan Iminitoff, Tamara Beck, Sue Haupt, Yifang Hu, Rose E. May, Lachlan Whitehead, Lin Tai, William Chiang, Marco J. Herold, Ygal Haupt, Gordon K. Smyth, Tim Thomas, Marnie E. Blewitt, Andreas Strasser, Anne K. Voss
Published 2019-04-01