Niacin: an old lipid drug in a new NAD+ dress

by Mario Romani, Dina Carina Hofer, Elena Katsyuba, Johan Auwerx
Published 2019-04-01

Selective cyclo-oxygenase-2 inhibitors impair adipocyte differentiation through inhibition of the clonal expansion phase

by Lluis Fajas, Stéphanie Miard, Michael R. Briggs, Johan Auwerx
Published 2003-09-01

NCoR1 Protects Mice From Dextran Sodium Sulfate–Induced Colitis by Guarding Colonic Crypt Cells From Luminal InsultSummary

by Elvira Mennillo, Xiaojing Yang, Miles Paszek, Johan Auwerx, Christopher Benner, Shujuan Chen
Published 2020-01-01

Cross-species functional modules link proteostasis to human normal aging.

by Andrea Komljenovic, Hao Li, Vincenzo Sorrentino, Zoltán Kutalik, Johan Auwerx, Marc Robinson-Rechavi
Published 2019-07-01

GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells

by Marina Besprozvannaya, Eamonn Dickson, Hao Li, Kenneth S Ginburg, Donald M Bers, Johan Auwerx, Jodi Nunnari
Published 2018-02-01

The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress

by Olli Matilainen, Maroun S. Bou Sleiman, Pedro M. Quiros, Susana M. D. A. Garcia, Johan Auwerx
Published 2017-11-01

Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections

by Eleonora Ciarlo, Tytti Heinonen, Jérôme Lugrin, Hans Acha-Orbea, Didier Le Roy, Johan Auwerx, Thierry Roger
Published 2017-06-01

An evolutionarily conserved role for the aryl hydrocarbon receptor in the regulation of movement.

by Evan G Williams, Laurent Mouchiroud, Michael Frochaux, Ashutosh Pandey, Pénélope A Andreux, Bart Deplancke, Johan Auwerx
Published 2014-09-01

Autophagy defect is associated with low glucose-induced apoptosis in 661W photoreceptor cells.

by Delphine Balmer, Martine Emery, Pénélope Andreux, Johan Auwerx, Vanessa Ginet, Julien Puyal, Daniel F Schorderet, Raphaël Roduit
Published 2013-01-01

Label-free three-dimensional imaging of Caenorhabditis elegans with visible optical coherence microscopy.

by Séverine Coquoz, Paul J Marchand, Arno Bouwens, Laurent Mouchiroud, Vincenzo Sorrentino, Daniel Szlag, Johan Auwerx, Theo Lasser
Published 2017-01-01

Reversible and long-term immobilization in a hydrogel-microbead matrix for high-resolution imaging of Caenorhabditis elegans and other small organisms.

by Li Dong, Matteo Cornaglia, Gopalan Krishnamani, Jingwei Zhang, Laurent Mouchiroud, Thomas Lehnert, Johan Auwerx, Martin A M Gijs
Published 2018-01-01

LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome.

by Philippe Boucher, Wei-Ping Li, Rachel L Matz, Yoshiharu Takayama, Johan Auwerx, Richard G W Anderson, Joachim Herz
Published 2007-05-01

SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis.

by Giuseppe Lo Sasso, Keir Joe Menzies, Adrienne Mottis, Alessandra Piersigilli, Alessia Perino, Hiroyasu Yamamoto, Kristina Schoonjans, Johan Auwerx
Published 2014-01-01

Specification of haematopoietic stem cell fate via modulation of mitochondrial activity

by Nicola Vannini, Mukul Girotra, Olaia Naveiras, Gennady Nikitin, Vasco Campos, Sonja Giger, Aline Roch, Johan Auwerx, Matthias P. Lutolf
Published 2016-10-01

NR5A2 regulates Lhb and Fshb transcription in gonadotrope-like cells in vitro, but is dispensable for gonadotropin synthesis and fertility in vivo.

by Jérôme Fortin, Vikas Kumar, Xiang Zhou, Ying Wang, Johan Auwerx, Kristina Schoonjans, Ulrich Boehm, Derek Boerboom, Daniel J Bernard
Published 2013-01-01

The carboxy-terminal region of human lipoprotein lipase is necessary for its exit from the endoplasmic reticulum

by Roser Buscà, Mònica Martínez, Elisabet Vilella, Julia Peinado, Josep Lluis Gelpi, Samir Deeb, Johan Auwerx, Manuel Reina, Senén Vilaró
Published 1998-04-01

PPARγ ligands switched high fat diet-induced macrophage M2b polarization toward M2a thereby improving intestinal Candida elimination.

by Lise Lefèvre, Amandine Galès, David Olagnier, José Bernad, Laurence Perez, Rémy Burcelin, Alexis Valentin, Johan Auwerx, Bernard Pipy, Agnès Coste
Published 2010-01-01

An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolism

by Dennis Dahlmans, Alexandre Houzelle, Pénélope Andreux, Johanna A. Jörgensen, Xu Wang, Leon J. de Windt, Patrick Schrauwen, Johan Auwerx, Joris Hoeks
Published 2017-11-01

Diet modulates cecum bacterial diversity and physiological phenotypes across the BXD mouse genetic reference population.

by Maria Elisa Perez-Munoz, Autumn M McKnite, Evan G Williams, Johan Auwerx, Robert W Williams, Daniel A Peterson, Daniel C Ciobanu
Published 2019-01-01

Ppargamma2 is a key driver of longevity in the mouse.

by Carmen Argmann, Radu Dobrin, Sami Heikkinen, Aurélie Auburtin, Laurent Pouilly, Terrie-Anne Cock, Hana Koutnikova, Jun Zhu, Eric E Schadt, Johan Auwerx
Published 2009-12-01