Emerging Next-Generation Target for Cancer Immunotherapy Research: The Orphan Nuclear Receptor NR2F6

by Victoria Klepsch, Kerstin Siegmund, Gottfried Baier
Published 2021-05-01

Nuclear Receptors Regulate Intestinal Inflammation in the Context of IBD

by Victoria Klepsch, Alexander R. Moschen, Herbert Tilg, Gottfried Baier, Natascha Hermann-Kleiter
Published 2019-05-01

Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy

by Victoria Klepsch, Maria Pommermayr, Dominik Humer, Natascha Brigo, Natascha Hermann-Kleiter, Gottfried Baier
Published 2020-01-01

Loss-of-function phenotype of a PKCθT219A knockin mouse strain

by Nikolaus Thuille, Kerstin Siegmund, Victoria Klepsch, Jacqueline Schörgenhuber, Sarah Danklmaier, Michael Leitges, Gottfried Baier
Published 2019-11-01

Orphan Nuclear Receptor NR2F6 Suppresses T Follicular Helper Cell Accumulation through Regulation of IL-21

by William J. Olson, Bojana Jakic, Verena Labi, Katia Schoeler, Michaela Kind, Victoria Klepsch, Gottfried Baier, Natascha Hermann-Kleiter
Published 2019-09-01

Loss of the orphan nuclear receptor NR2F6 enhances CD8+ T-cell memory via IFN-γ

by Bojana Jakic, William J. Olson, Kerstin Siegmund, Victoria Klepsch, Janine Kimpel, Verena Labi, Dietmar Zehn, Gottfried Baier, Natascha Hermann-Kleiter
Published 2021-02-01

Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution

by Mirjana Efremova, Dietmar Rieder, Victoria Klepsch, Pornpimol Charoentong, Francesca Finotello, Hubert Hackl, Natascha Hermann-Kleiter, Martin Löwer, Gottfried Baier, Anne Krogsdam, Zlatko Trajanoski
Published 2018-01-01

Iron Supplementation Interferes With Immune Therapy of Murine Mammary Carcinoma by Inhibiting Anti-Tumor T Cell Function

by Piotr Tymoszuk, Manfred Nairz, Natascha Brigo, Verena Petzer, Simon Heeke, Brigitte Kircher, Natascha Hermann-Kleiter, Victoria Klepsch, Igor Theurl, Günter Weiss, Günter Weiss, Christa Pfeifhofer-Obermair
Published 2020-12-01

The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance

by Natascha Hermann-Kleiter, Victoria Klepsch, Stephanie Wallner, Kerstin Siegmund, Sebastian Klepsch, Selma Tuzlak, Andreas Villunger, Sandra Kaminski, Christa Pfeifhofer-Obermair, Thomas Gruber, Dominik Wolf, Gottfried Baier
Published 2015-09-01

Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade

by Victoria Klepsch, Natascha Hermann-Kleiter, Patricia Do-Dinh, Bojana Jakic, Anne Offermann, Mirjana Efremova, Sieghart Sopper, Dietmar Rieder, Anne Krogsdam, Gabriele Gamerith, Sven Perner, Alexandar Tzankov, Zlatko Trajanoski, Dominik Wolf, Gottfried Baier
Published 2018-04-01