The Generation of an Engineered Interleukin-10 Protein With Improved Stability and Biological Function

by Faisal Minshawi, Faisal Minshawi, Sebastian Lanvermann, Edward McKenzie, Rebecca Jeffery, Kevin Couper, Stamatia Papoutsopoulou, Stamatia Papoutsopoulou, Axel Roers, Werner Muller
Published 2020-08-01

Can harmonisation of outcomes bridge the translation gap for pre-clinical research? A systematic review of outcomes measured in mouse models of type 2 diabetes

by Nicola L. Harman, Adrián Sanz-Moreno, Stamatia Papoutsopoulou, Katie A. Lloyd, Kamar E. Ameen-Ali, Malcolm Macleod, Paula R. Williamson
Published 2020-12-01

Impact of Interleukin 10 Deficiency on Intestinal Epithelium Responses to Inflammatory Signals

by Stamatia Papoutsopoulou, Stamatia Papoutsopoulou, Liam Pollock, Catherine Walker, William Tench, Sakim Shakh Samad, François Bergey, Luca Lenzi, Raheleh Sheibani-Tezerji, Phillip Rosenstiel, Mohammad Tauqeer Alam, Mohammad Tauqeer Alam, Vitor A. P. Martins Dos Santos, Vitor A. P. Martins Dos Santos, Werner Müller, Barry J. Campbell
Published 2021-06-01

Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

by Stamatia Papoutsopoulou, Stamatia Papoutsopoulou, Michael D. Burkitt, François Bergey, Hazel England, Rachael Hough, Lorraine Schmidt, David G. Spiller, Michael H. R. White, Pawel Paszek, Dean A. Jackson, Vitor A. P. Martins Dos Santos, Vitor A. P. Martins Dos Santos, Gernot Sellge, D. Mark Pritchard, Barry J. Campbell, Werner Müller, Chris S. Probert
Published 2019-09-01

TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control TH2-Mediated Immunopathology.

by Yashaswini Kannan, Jimena Perez-Lloret, Yanda Li, Lewis J Entwistle, Hania Khoury, Stamatia Papoutsopoulou, Radma Mahmood, Nuha R Mansour, Stanley Ching-Cheng Huang, Edward J Pearce, Luiz Pedro S de Carvalho, Steven C Ley, Mark S Wilson
Published 2016-08-01

Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine TumorsSummary

by Katie A. Lloyd, Bryony N. Parsons, Michael D. Burkitt, Andrew R. Moore, Stamatia Papoutsopoulou, Malcolm Boyce, Carrie A. Duckworth, Klaire Exarchou, Nathan Howes, Lucille Rainbow, Yongxiang Fang, Claus Oxvig, Steven Dodd, Andrea Varro, Neil Hall, D. Mark Pritchard
Published 2020-01-01

Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease

by Katie Lloyd, Stamatia Papoutsopoulou, Emily Smith, Philip Stegmaier, Francois Bergey, Lorna Morris, Madeleine Kittner, Hazel England, Dave Spiller, Mike H. R. White, Carrie A. Duckworth, Barry J. Campbell, Vladimir Poroikov, Vitor A. P. Martins dos Santos, Alexander Kel, Werner Muller, D. Mark Pritchard, Chris Probert, Michael D. Burkitt, The SysmedIBD Consortium
Published 2020-11-01