Phylogenetic analysis of vitamin B12-related metabolism in Mycobacterium tuberculosis

by Douglas B. Young, Iñaki eComas, Luiz Pedro Sorio de Carvalho
Published 2015-03-01

Flexible nitrogen utilisation by the metabolic generalist pathogen Mycobacterium tuberculosis

by Aleksandra Agapova, Agnese Serafini, Michael Petridis, Debbie M Hunt, Acely Garza-Garcia, Charles D Sohaskey, Luiz Pedro Sório de Carvalho
Published 2019-01-01

Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes

by Dimitrios Evangelopoulos, Gareth A. Prosser, Angela Rodgers, Belinda M. Dagg, Bhagwati Khatri, Mei Mei Ho, Maximiliano G. Gutierrez, Teresa Cortes, Luiz Pedro S. de Carvalho
Published 2019-09-01

Uncoupling conformational states from activity in an allosteric enzyme

by João P. Pisco, Cesira de Chiara, Kamila J. Pacholarz, Acely Garza-Garcia, Roksana W. Ogrodowicz, Philip A. Walker, Perdita E. Barran, Stephen J. Smerdon, Luiz Pedro S. de Carvalho
Published 2017-08-01

TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control TH2-Mediated Immunopathology.

by Yashaswini Kannan, Jimena Perez-Lloret, Yanda Li, Lewis J Entwistle, Hania Khoury, Stamatia Papoutsopoulou, Radma Mahmood, Nuha R Mansour, Stanley Ching-Cheng Huang, Edward J Pearce, Luiz Pedro S de Carvalho, Steven C Ley, Mark S Wilson
Published 2016-08-01

Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

by Sarah Batson, Cesira de Chiara, Vita Majce, Adrian J. Lloyd, Stanislav Gobec, Dean Rea, Vilmos Fülöp, Christopher W. Thoroughgood, Katie J. Simmons, Christopher G. Dowson, Colin W. G. Fishwick, Luiz Pedro S. de Carvalho, David I. Roper
Published 2017-12-01

Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.

by Alexandre Gouzy, Gérald Larrouy-Maumus, Daria Bottai, Florence Levillain, Alexia Dumas, Joshua B Wallach, Irène Caire-Brandli, Chantal de Chastellier, Ting-Di Wu, Renaud Poincloux, Roland Brosch, Jean-Luc Guerquin-Kern, Dirk Schnappinger, Luiz Pedro Sório de Carvalho, Yannick Poquet, Olivier Neyrolles
Published 2014-02-01

Design and Synthesis of Imidazole and Triazole Pyrazoles as Mycobacterium Tuberculosis CYP121A1 Inhibitors

by Dr. Safaa M. Kishk, Dr. Kirsty J. McLean, Dr. Sakshi Sood, Darren Smith, Jack W.D. Evans, Prof. Mohamed A. Helal, Prof. Mohamed S. Gomaa, Prof. Ismail Salama, Prof. Samia M. Mostafa, Dr. Luiz Pedro S. de Carvalho, Colin W. Levy, Prof. Andrew W. Munro, Dr. Claire Simons
Published 2019-07-01