Effects of cigarette smoke on barrier function and tight junction proteins in the bronchial epithelium: protective role of cathelicidin LL-37

Effects of cigarette smoke on barrier function and tight junction proteins in the bronchial epithelium: protective role of cathelicidin LL-37

Abstract Background Airway epithelial barrier function is maintained by the formation of tight junctions (TJs) and adherens junctions (AJs). Inhalation of cigarette smoke causes airway epithelial barrier dysfunction and may contribute to the pathogenesis of chronic lung diseases such as asthma and c...

Full description

Bibliographic Details
Main Authors: Miyoko Tatsuta, Keiko Kan-o, Yumiko Ishii, Norio Yamamoto, Tomohiro Ogawa, Satoru Fukuyama, Aimi Ogawa, Akitaka Fujita, Yoichi Nakanishi, Koichiro Matsumoto
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Respiratory Research
Subjects:
Airway epithelial barrier function
Cigarette smoke
Glucocorticosteroid
Long-acting β2-agonist
Cathelicidin
LL-37
Online Access:http://link.springer.com/article/10.1186/s12931-019-1226-4

Internet

http://link.springer.com/article/10.1186/s12931-019-1226-4

Similar Items