Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells.

Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells.

Salinomycin raised hope to be effective in anti-cancer therapies due to its capability to overcome apoptosis-resistance in several types of cancer cells. Recently, its effectiveness against human hepatocellular carcinoma (HCC) cells both in vitro and in vivo was demonstrated. However, the mechanism...

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Bibliographic Details
Main Authors: Johannes Klose, Metodi V Stankov, Moritz Kleine, Wolf Ramackers, Diana Panayotova-Dimitrova, Mark D Jäger, Jürgen Klempnauer, Michael Winkler, Hüseyin Bektas, Georg M N Behrens, Florian W R Vondran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24816744/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24816744/pdf/?tool=EBI

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