Single Low Dose Primaquine (0.25 mg/kg) Does Not Cause Clinically Significant Haemolysis in G6PD Deficient Subjects.

Single Low Dose Primaquine (0.25 mg/kg) Does Not Cause Clinically Significant Haemolysis in G6PD Deficient Subjects.

Primaquine is the only drug consistently effective against mature gametocytes of Plasmodium falciparum. The transmission blocking dose of primaquine previously recommended was 0.75 mg/kg (adult dose 45 mg) but its deployment was limited because of concerns over haemolytic effects in patients with gl...

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Bibliographic Details
Main Authors: Germana Bancone, Nongnud Chowwiwat, Raweewan Somsakchaicharoen, Lalita Poodpanya, Paw Khu Moo, Gornpan Gornsawun, Ladda Kajeechiwa, May Myo Thwin, Santisuk Rakthinthong, Suphak Nosten, Suradet Thinraow, Slight Naw Nyo, Clare L Ling, Jacher Wiladphaingern, Naw Lily Kiricharoen, Kerryn A Moore, Nicholas J White, Francois Nosten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4807095?pdf=render

Internet

http://europepmc.org/articles/PMC4807095?pdf=render

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