Protective effects of astragaloside IV against hypertension-induced vascular remodeling involves the DNMT1 and TET2 signaling pathway

Proliferation, migration, and the phenotypic switch of vascular smooth muscle cells (VSMCs) play an important role in vascular remodeling induced by hypertension. Astragaloside IV (AS-IV), the active ingredient of Astragalus membranaceus, has been shown to exert a beneficial role in cardiovascular d...

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Bibliographic Details
Main Authors: Qin Yingchun, Xie Yilin, Li Aihua, Zhang Xiaoqin, Yan Zhiqiang
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2021-01-01
Series:Archives of Biological Sciences
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2021/0354-46642100024Q.pdf