Characterization of Novel Murine and Human PDAC Cell Models: Identifying the Role of Intestine Specific Homeobox Gene ISX in Hypoxia and Disease Progression

Characterization of Novel Murine and Human PDAC Cell Models: Identifying the Role of Intestine Specific Homeobox Gene ISX in Hypoxia and Disease Progression

Therapy failure and metastasis-associated mortality are stumbling blocks in the management of PDAC in patients. Failure of therapy is associated to intense hypoxic conditions of tumors. To develop effective therapies, a complete understanding of hypoxia-associated changes in genetic landscape of tum...

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Bibliographic Details
Main Authors: Arsheed A. Ganaie, Aijaz Parray, Tabish Hussain, Ashraf Shabaneh, Anmbreen Jamroze, Marina G. Ferrari, Lei Wang, D. Joshua Liao, Shahriar Koochekpour, Sanjeev Nanda, Jinhua Wang, Yibin Deng, Sergio A Gradilone, Edward H. Hinchcliffe, Badrinath R. Konety, Mohammad Saleem
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523319301822

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http://www.sciencedirect.com/science/article/pii/S1936523319301822

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