Characterization of a murine model of SMA

Characterization of a murine model of SMA

Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease, which is the leading genetic cause of mortality in children. To date no effective treatment exists for SMA. The genetic basis for SMA has been well documented as a mutation in the gene for survival of motor neuron (SMN)....

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Bibliographic Details
Main Authors: Eleanor M. Donnelly, Eric T. Quach, Terence M. Hillery, Brenten L. Heeke, Brooke R. Snyder, Chalonda R. Handy, Deirdre M. O'Connor, Nicholas M. Boulis, Thais Federici
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Neurobiology of Disease
Subjects:
Spinal muscular atrophy
Animal model
Behavioral
Neuromuscular disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111003937

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http://www.sciencedirect.com/science/article/pii/S0969996111003937

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