Design and in vitro evaluation of layer by layer siRNA nanovectors targeting breast tumor initiating cells.

Efficient therapeutics and early detection has helped to increase breast cancer survival rates over the years. However, the recurrence of breast cancer remains to be a problem and this may be due to the presence of a small population of cells, called tumor initiating cells (TICs). Breast TICs are re...

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Bibliographic Details
Main Authors: Hamsa Jaganathan, Sucharita Mitra, Srimeenakshi Srinivasan, Bhuvanesh Dave, Biana Godin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3973666?pdf=render