Temporal expression profiles of lncRNA and mRNA in human embryonic stem cell-derived motor neurons during differentiation

Background Human embryonic stem cells (hESC) have been an invaluable research tool to study motor neuron development and disorders. However, transcriptional regulation of multiple temporal stages from ESCs to spinal motor neurons (MNs) has not yet been fully elucidated. Thus, the goals of this study...

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Bibliographic Details
Main Authors: Xue-Jiao Sun, Ming-Xing Li, Chen-Zi Gong, Jing Chen, Mohammad Nasb, Sayed Zulfiqar Ali Shah, Muhammad Rehan, Ya-Jie Li, Hong Chen
Format: Article
Language:English
Published: PeerJ Inc. 2020-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/10075.pdf