Dietary Bile Acids Enhance Growth, and Alleviate Hepatic Fibrosis Induced by a High Starch Diet via AKT/FOXO1 and cAMP/AMPK/SREBP1 Pathway in Micropterus salmoides

Dietary Bile Acids Enhance Growth, and Alleviate Hepatic Fibrosis Induced by a High Starch Diet via AKT/FOXO1 and cAMP/AMPK/SREBP1 Pathway in Micropterus salmoides

A 10-week feeding trial was conducted to investigate the effects of dietary bile acids (BA) on growth, glucose and lipid metabolism, liver histopathology, and the underlying regulation mechanism on AKT/FOXO1 (forkhead box O1) and cAMP/AMPK/SREBP1 (sterol regulatory element-binding protein 1) pathway...

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Bibliographic Details
Main Authors: Huanhuan Yu, Lulu Zhang, Pei Chen, Xiaofang Liang, Aizhi Cao, Juan Han, Xiufeng Wu, Yinhua Zheng, Yuchang Qin, Min Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Physiology
Subjects:
bile acids
inflammation
apoptosis
liver health
glucose and lipid metabolism
Micropterus salmoides
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01430/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01430/full

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