Poloxamer-Based Thermoreversible Gel for Topical Delivery of Emodin: Influence of P407 and P188 on Solubility of Emodin and Its Application in Cellular Activity Screening

Poloxamer-Based Thermoreversible Gel for Topical Delivery of Emodin: Influence of P407 and P188 on Solubility of Emodin and Its Application in Cellular Activity Screening

Emodin is a component in a Chinese herb, Rheum officinale Baill, traditionally used for diabetes and anticancer. Its poor solubility is one of the major challenges to pharmaceutical scientists. We previously reported on thermoreversible gel formulations based on poloxamer for the topical delivery of...

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Bibliographic Details
Main Authors: Eunmi Ban, Mijung Park, Seonghee Jeong, Taekhyun Kwon, Eun-Hee Kim, Kiwon Jung, Aeri Kim
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Molecules
Subjects:
thermoreversible
poloxamer
emodin
solubility
in vitro cellular activity screening
Online Access:http://www.mdpi.com/1420-3049/22/2/246

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http://www.mdpi.com/1420-3049/22/2/246

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