Human omental-derived adipose stem cells increase ovarian cancer proliferation, migration, and chemoresistance.

Adipose tissue contains a population of multipotent adipose stem cells (ASCs) that form tumor stroma and can promote tumor progression. Given the high rate of ovarian cancer metastasis to the omental adipose, we hypothesized that omental-derived ASC may contribute to ovarian cancer growth and dissem...

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Bibliographic Details
Main Authors: Aleksandra Nowicka, Frank C Marini, Travis N Solley, Paula B Elizondo, Yan Zhang, Hadley J Sharp, Russell Broaddus, Mikhail Kolonin, Samuel C Mok, Melissa S Thompson, Wendy A Woodward, Karen Lu, Bahar Salimian, Deepak Nagrath, Ann H Klopp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3847080?pdf=render