Novel genome polymorphisms in BCG vaccine strains and impact on efficacy

<p>Abstract</p> <p>Bacille Calmette-Guérin (BCG) is an attenuated strain of <it>Mycobacterium bovis </it>currently used as a vaccine against tuberculosis. Global distribution and propagation of BCG has contributed to the <it>in vitro </it>evolution of the va...

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Bibliographic Details
Main Authors: Gao George, Alexander David C, Yu Xuping, Wu Zuowei, Tran Vanessa, Leung Andrea S, Zhu Baoli, Liu Jun
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/413