TNF-α Producing Innate Lymphoid Cells (ILCs) Are Increased in Active Celiac Disease and Contribute to Promote Intestinal Atrophy in Mice.

Innate lymphoid cells (ILCs) are an emerging family of innate hematopoietic cells producing inflammatory cytokines and involved in the pathogenesis of several immune-mediated diseases. The aim of this study was to characterize the tissue distribution of ILCs in celiac disease (CD), a gluten-driven e...

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Bibliographic Details
Main Authors: Irene Marafini, Ivan Monteleone, Davide Di Fusco, Maria Laura Cupi, Omero Alessandro Paoluzi, Alfredo Colantoni, Angela Ortenzi, Roberta Izzo, Simone Vita, Elisabetta De Luca, Giuseppe Sica, Francesco Pallone, Giovanni Monteleone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4423916?pdf=render