Guaiazulene Triggers ROS-Induced Apoptosis and Protective Autophagy in Non-small Cell Lung Cancer

Guaiazulene Triggers ROS-Induced Apoptosis and Protective Autophagy in Non-small Cell Lung Cancer

Non-small cell lung cancer (NSCLC) is one of the most frequent cancers worldwide, yet effective treatment remains a clinical challenge. Guaiazulene (GYZ), a cosmetic color additive, has previously been characterized as a potential antitumor agent due to observed anticancer effects. However, the effi...

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Bibliographic Details
Main Authors: Qin Ye, Li Zhou, Ping Jin, Lei Li, Shuwen Zheng, Zhao Huang, Jiayang Liu, Siyuan Qin, Hao Liu, Bingwen Zou, Ke Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
guaiazulene
autophagy
non-small cell lung cancer
AKT/mTOR
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.621181/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.621181/full

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