Investigating Biological Activity Spectrum for Novel Styrylquinazoline Analogues

Investigating Biological Activity Spectrum for Novel Styrylquinazoline Analogues

In this study, series of ring-substituted 2-styrylquinazolin-4(3H)-one and 4-chloro-2-styrylquinazoline derivatives were prepared. The syntheses of the discussed compounds are presented. The compounds were analyzed by RP-HPLC to determine lipophilicity. They were tested for their inhibitory activity...

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Bibliographic Details
Main Authors: Jaroslaw Polanski, Jiri Dohnal, Jim O'Mahony, Aidan Coffey, Marcela Vejsova, James Carroll, Katarina Kralova, Matus Pesko, Robert Musiol, Jacek Finster, Josef Jampilek
Format: Article
Language:English
Published: MDPI AG 2009-10-01
Series:Molecules
Subjects:
styrylquinazolinone and styrylquinazoline derivatives
lipophilicity
PET inhibition
spinach chloroplasts
in vitro antimycobacterial activity
in vitro antifungal activity
structure-activity relationships
Online Access:http://www.mdpi.com/1420-3049/14/10/4246/

Internet

http://www.mdpi.com/1420-3049/14/10/4246/

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