Umbilical cord-derived mesenchymal stem cells on scaffolds facilitate collagen degradation via upregulation of MMP-9 in rat uterine scars

Umbilical cord-derived mesenchymal stem cells on scaffolds facilitate collagen degradation via upregulation of MMP-9 in rat uterine scars

Abstract Background Severe injuries of the uterus may trigger uterine scar formation, ultimately leading to infertility or obstetrical complications. To date, few methods have adequately solved the problem of collagen deposition in uterine scars. Umbilical cord-derived mesenchymal stem cells (UC-MSC...

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Bibliographic Details
Main Authors: Lu Xu, Lijun Ding, Lei Wang, Yun Cao, Hui Zhu, Jingjie Lu, Xin’an Li, Tianran Song, Yali Hu, Jianwu Dai
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Stem Cell Research & Therapy
Subjects:
UC-MSCs
Scaffolds
Uterine scars
MMP-9
Fertility
Online Access:http://link.springer.com/article/10.1186/s13287-017-0535-0

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http://link.springer.com/article/10.1186/s13287-017-0535-0

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