INDUCTION OF EPITHELIAL-TO-MESENCHYMAL TRANSITION IN MCF-7-SNAI1 CELLS LEADS TO REORGANIZATION OF ADHERENS JUNCTIONS AND ACQUISITION OF MIGRATORY ACTIVITY

Using DIC and confocal microscopy, changes in morphology, migratory characteristics and adherence junctions (AJs) were analyzed in the mammary carcinoma cell line MCF-7-SNAI1  after activation of the EMT transcription factor SNAI1. Western Blot analysis showed that  after removal of tetracycline fro...

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Bibliographic Details
Main Authors: I. Y. Zhitnyak, N. I. Litovka, S. N. Rubtsova, N. A. Gloushankova
Format: Article
Language:Russian
Published: Tomsk National Research Medical Center of the Russian Academy of Sciences 2018-09-01
Series:Sibirskij Onkologičeskij Žurnal
Subjects:
Online Access:https://www.siboncoj.ru/jour/article/view/811